International journal of pharmaceuticsHumansInflammatory Bowel DiseasesColonIntestinal MucosaTumor Necrosis Factor-alpha
Functional and morphological characterisation of human colonoid-derived monolayers under inflammatory conditions.
Inês A Parente, Linda Chiara, Lisa Flammini, Martina Viglioli, Federica Vacondio, Federica Gaiani, Gian Luigi de'Angelis, Marco Pagano Mariano, Silvia La Monica, Elisabetta Barocelli, Simona Bertoni
Published: 202510.1016/j.ijpharm.2025.126228
Abstract
Despite progress in the diagnosis and treatment of inflammatory bowel disease (IBD), its incidence and prevalence continue to rise. The lack of human preclinical models limits the ability to study disease mechanisms and develop effective therapies. H…
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