International journal of infectious diseases : IJID : official publication of the International Society for Infectious DiseasesHaemophilus influenzaeMicrobial Sensitivity TestsAnti-Bacterial AgentsMutationHumans
A novel mechanism of unstable heteroresistance via reversible ompP2 mutations in Haemophilus influenzae.
Sabine Petersen, Margo Diricks, Christian Utpatel, Hinrich Schulenburg, Matthias Merker
Published: 202510.1016/j.ijid.2025.108178
Abstract
OBJECTIVES: Heteroresistance, the presence of a resistant subpopulation within a predominantly susceptible bacterial isolate, is usually difficult to detect and can cause treatment failure. Mechanisms driving unstable heteroresistant phenotypes, whic…
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