International journal of cardiology
Non-invasive evaluation of left ventricular hemodynamic force abnormalities in hypertrophic cardiomyopathy: Implications for myosin inhibition.
Chiara Zocchi, Alessandra Milazzo, Giorgia Panichella, Manuel Garofalo, Angela I Fanizzi, Maddalena Ragagnin, Raffaele Coppini, Raymond H Chan, Mattia Zampieri, Francesco Cappelli, Maurizio Pieroni, Gianni Pedrizzetti, Iacopo Olivotto, Annamaria Del Franco
Published: 202610.1016/j.ijcard.2026.134175
Abstract
BACKGROUND: Hypertrophic cardiomyopathy (HCM) is characterized by abnormal myocardial mechanics, with or without left ventricular outflow tract obstruction (LVOTO). Myosin inhibitors such as mavacamten have shown clinical efficacy in reducing obstruc…
Preview only. Read the full abstract at the source