International journal of biological macromoleculesHyaluronic AcidHydrogelsGlutamic AcidCytoskeletonPolylysine
Cell exposure to hyaluronic acid/ε-Poly-l-Lysine physically crosslinked hydrogel disrupts glutamate metabolism and leads to cytoskeletal collapse.
Jingzhi Fan, Vahid Jahed, Liva Vita Kaufmane, Lilite Sadovska, Annija Vaska, Oleksandr Pogorielov, Rinalds Serzants, Dagnija Loca, Aija Line, Antons Sizovs, Kristaps Klavins
Published: 202610.1016/j.ijbiomac.2025.149982
Abstract
The multifunctional hydrogels made from hyaluronic acid (HA) and ε-poly-l-lysine (PLL) are interesting for soft tissue regeneration and antibacterial use. However, despite their strong antibacterial properties, the biocompatibility of physically cros…
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