International journal of biological macromolecules
Isobavachalcone reduces blood glucose and promotes muscle development via dipeptidyl peptidase-4 inhibition.
Eun Ju Lee, Sibhghatulla Shaikh, Khurshid Ahmad, Si Han Lee, Jae-Moon Choi, Yong Ho Lee, Inho Choi
Published: 202510.1016/j.ijbiomac.2025.149858
Abstract
Glucagon-like peptide-1 (GLP-1) regulates insulin secretion; however, GLP-1 is rapidly degraded by dipeptidyl peptidase-4 (DPP4). Synthetic DPP4 inhibitors are used to treat type 2 diabetes (T2D); however, safer alternatives are required owing to the…
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