International journal of biological macromoleculesHumansCartilage Oligomeric Matrix ProteinAnimalsProtein MultimerizationExtracellular Matrix
Unique structural features of the pentameric matrix protein COMP sustain its dynamic regulation of extra- and intracellular activities: A review.
Erika Boiardi, Simona Demmi, Graziana Tittaferrante, Mirca Lazzaretti, Giorgio Malpeli, Giorgia Brancolini, Roberto Perris
Published: 202610.1016/j.ijbiomac.2025.149728
Abstract
The macromolecule COMP -Cartilage Oligomeric Matrix Protein- was originally discovered as an essential regulator of the assembly, integrity and homeostatic remodeling of cartilage tissue ECMs. Later, however, it was found to have a more widespread di…
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