International journal of biological macromoleculesHumansAntibodiesMonoclonalEpitopesReceptors
Molecular basis of CD155-mediated immune regulation revealed by a novel epitope-specific human monoclonal antibody.
Jae Hyeon Hwang, Ji Hyun Lee, Kyusang Hwang, Yonghee Lee, Younggyun Han, Jin Young Song, Hyunbo Shim, Michael Lim, Sukmook Lee
Published: 202610.1016/j.ijbiomac.2025.149602
Abstract
CD155 overexpression in cancers functions as an emerging immune checkpoint that enables tumor cells to evade immune surveillance, underscoring the necessity for novel therapeutic strategies. In this study, four fully human monoclonal antibodies (mAbs…
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