International journal of biological macromoleculesEscherichia coli O157Methicillin-Resistant Staphylococcus aureusCell WallCell MembraneReactive Oxygen Species
Bacteriophage lysin P26ly combats multidrug-resistant Escherichia coli O157 and methicillin-resistant Staphylococcus aureus via cell wall degradation and membrane disruption.
Gui-Si Zhu, Xiao-Xue Yang, Yao Zhang, Xin-Yuan Zhang, Lian-Bing Lin, Feng Wang
Published: 202610.1016/j.ijbiomac.2025.149288
Abstract
To address the growing challenge of antimicrobial resistance, we evaluated P26ly, a novel 17-kDa lysin derived from Shigella-infecting phage DS8 with a conserved lambda_lys-like domain. The antimicrobial effects of P26ly were assessed via turbidimetr…
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