International journal of biological macromoleculesArthritisRheumatoidFibroblastsHumansAnimals
H3K18la-driven methyltransferase 1-mediated upregulation of NeuroD1 m7G modification in promoting ferroptosis resistance in rheumatoid arthritis synovial fibroblasts.
Yayun Xu, Wenqiang Liu, Zhuoyan Zai, Xuewen Qian, Weirong Hu, Xiaoqing Peng, Feihu Chen
Published: 202610.1016/j.ijbiomac.2025.149196
Abstract
Activated rheumatoid arthritis synovial fibroblasts (RASFs) exhibit hyperplasia that significantly contributes to rheumatoid arthritis (RA)-related joint destruction. Lactate, previously considered merely a byproduct of glycolysis, is now recognized…
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