International journal of biological macromoleculesCarcinomaHepatocellularLiver NeoplasmsHumansYAP-Signaling Proteins
Laminin β1 stimulates the Hippo-YAP1 pathway to advance the progression and lenvatinib resistance in hepatocellular carcinoma.
Zhiliang Cai, Jinjin Li, Long Wu, Xinyi Hu, Wanying Lin, Bin Peng, Haoming Chen, Qing Yang, Bo Li, Guobang Li, Fen Cao
Published: 202610.1016/j.ijbiomac.2025.149150
Abstract
Hepatocellular carcinoma (HCC) is one of the most common and fatal solid cancers worldwide, particularly in Asian countries. Alterations in extracellular matrix (ECM) contribute to HCC development, yet the precise underlying mechanisms remain unclear…
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