International journal of biological macromoleculesHumansCalcitonin Gene-Related PeptideCalcitonin Gene-Related Peptide Receptor AntagonistsReceptorsMolecular Docking Simulation
Mimotopes of calcitonin gene-related peptide (CGRP) screened from Fv-antibody library: antagonists to CGRP receptor.
Jeong Soo Sung, Hyung Eun Bae, Min-Jung Kang, Joachim Jose, Misu Lee, Min Kyung Chu, Jae-Chul Pyun
Published: 202510.1016/j.ijbiomac.2025.149080
Abstract
Calcitonin gene-related peptide (CGRP) is a neuropeptide synthesized in the trigeminal ganglion and it has been identified as a key mediator in the pathophysiology of migraine. The monoclonal antibodies and small-molecule antagonists for calcitonin r…
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