International journal of biological macromoleculesHumansAnimalsFemaleBreast NeoplasmsCyclin-Dependent Kinase 4
Bovine serum albumin capped lipid nanosystem bearing CDK4/6 inhibitor to combat breast cancer: In-vitro and In-vivo assessment.
Mayur Aalhate, Srushti Mahajan, Rahul Kumar, Pooja Yadav, Anamika Sharma, Ujala Gupta, Indrani Maji, Anitha Sriram, Aditi Chitale, Madhav N Mugale, Manish K Chourasia, Pankaj Kumar Singh
Published: 202510.1016/j.ijbiomac.2025.148873
Abstract
Ribociclib (RIB) is a CDK4/6 inhibitor approved for the treatment of breast cancer. However, its BCS IV classification poses challenges in its delivery. The present research was aimed at developing bovine serum albumin (ALB) and Lipid-based nanocapsu…
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