International journal of biological macromoleculesEnzyme-Linked Immunosorbent AssayAnimalsAntibodiesMonoclonalHepatitis E virus
Sensitive detection of HEV antibodies using a blocking ELISA based on ORF2-specific monoclonal antibodies.
Haojie Wang, Yang Wu, Xing Liu, Bowen Shan, Lihong Xue, Yue Sun, Tongqing An, Changwen Li, Hongyan Chen, Xin Yin, Changqing Yu, Changyou Xia, He Zhang
Published: 202510.1016/j.ijbiomac.2025.148802
Abstract
Hepatitis E virus (HEV) is a significant zoonotic pathogen posing a global threat to both human and animal health. To advance broad-spectrum detection strategies for HEV, we developed high-affinity monoclonal antibodies targeting the conserved region…
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