International journal of biological macromoleculesFemaleHumansEmbryo ImplantationForkhead Box Protein O1Endometrium
Secretoglobin family 2A member 1 downregulation impairs endometrial decidualization in recurrent implantation failure by disrupting protein kinase B interaction and forkhead box O1 nuclear translocation.
Yan Zhou, Yuyang Liu, Juan Huang, Jingru Duan, Chenjia He, Meihan Xu, Xiaowei Zhou, Hanfei Zhu, Dan Zhang, Hsun-Ming Chang, Aijun Zhang, Bufang Xu
Published: 202510.1016/j.ijbiomac.2025.148658
Abstract
Embryo implantation requires precise endometrial receptivity, which is critically dependent on progesterone-induced stromal decidualization during the mid-secretory phase. In recurrent implantation failure (RIF), this process is impaired, yet the und…
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