International journal of biological macromoleculesCalciumGuanylate KinasesProtein BindingCalmodulinHumans
Structural basis for the Ca2+/CaM-mediated regulation of CASK-CaMK.
Wei Li, Yue Wang, Wei Feng
Published: 202510.1016/j.ijbiomac.2025.148495
Abstract
As a member of the Ca2+/CaM-dependent protein kinase family, CASK contains an N-terminal CaMK domain that is regulated by Ca2+-bound CaM, while the underlying mechanism remains to be elucidated. Here, we determine the crystal structures of CASK-CaMK…
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