International journal of biological macromoleculesSorafenibImidazolesBacterial ProteinsFusobacterium nucleatumPyridazines
Sorafenib and ponatinib as effective inhibitors of Fusobacterium nucleatum FtsZ: An in silico and in vitro study.
Hong Fang, Yan Jin, Mengyue Yang, Yongyuan Li, Youqun Shu, Zhenzhen Si, Zeying Cheng, Fanting Zhao, Hongmei Zhu, Yingqian Liu, Peng Chen
Published: 202510.1016/j.ijbiomac.2025.148363
Abstract
Drug repurposing is a promising strategy that involves re-evaluating the mechanisms of action of existing therapeutics, unlocking their potential for the treatment of other diseases, and expanding their indications. Fusobacterium nucleatum (F. nuclea…
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