International journal of biological macromoleculesMitochondrial ADPATP TranslocasesMolecular Dynamics SimulationBiological TransportHumans
Structural dynamics of the mitochondrial ADP/ATP carrier support an asymmetric transport mechanism.
Yunna Li, Qiuzi Yi, Yabing Cai, Yuchen Zhang, Jianchun Kong, Pingping Jiang, Xiaohui Cang
Published: 202510.1016/j.ijbiomac.2025.148348
Abstract
The mitochondrial ADP/ATP carrier (AAC) mediates ADP/ATP exchange across inner mitochondrial membrane via alternating between cytosol-open (c-) and matrix-open (m-) states. Despite the determination of crystallized structures for both states, its tra…
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