International journal of biological macromoleculesProtein StabilityProtein FoldingApoproteinsFlavodoxinTemperature
Protein thermostabilization with Protposer: Pushing the stability limits and folding reversibility of a highly-stabilized apoflavodoxin.
Antonio Hidalgo-Toledo, Darío Bazco, Víctor Correa-Pérez, Marta Martínez-Júlvez, Javier Sancho
Published: 202510.1016/j.ijbiomac.2025.148333
Abstract
Enhancing the stability of highly stable proteins represents an interesting challenge in protein design. We have used the computational tool Protposer to rapidly achieve large additional stabilization of apoflavodoxin, a protein strongly thermostabil…
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