International journal of biological macromoleculesArtemisia annuaArtemisininsFlavonoidsTranscription FactorsGene Expression Regulation
Integrated metabolomic and transcriptomic analysis reveals the coordinated regulatory mechanisms of artemisinin and flavonoid mediated by AaMYB8 in Artemisia annua.
Yiyang Han, Jingyi Liu, Yaojie Zhang, Yuxin Hou, Xiaowei Gao, Xueqing Fu, Pin Liu, Jingya Zhao, Kexuan Tang, Yuliang Wang
Published: 202510.1016/j.ijbiomac.2025.147998
Abstract
Artemisinin-based combination therapies are the first-line treatment for malaria, but artemisinin resistance has been reported in multiple regions. Studies suggest that Artemisia annua powder reverses drug resistance, with flavonoids in the plant bei…
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