International journal of antimicrobial agentsHumansTenofovirMicroRNAsMaleExosomes
Urinary exosome-derived microRNAs as biomarkers of tenofovir disoproxil fumarate (TDF)-induced renal toxicity in people with HIV-1.
José L Casado, Pilar Vizcarra, Francisco J Hernández-Walias, José Manuel Del Rey, Carmen Santiuste, Carmen Molano, Miriam Menacho, Alejandro Vallejo
Published: 202610.1016/j.ijantimicag.2025.107654
Abstract
OBJECTIVES: Tenofovir disoproxil fumarate (TDF) has been associated with proximal tubular renal toxicity, though the timing, severity, and long-term outcomes remain controversial. This study aimed to assess urinary exosome-derived microRNAs (miRNAs)…
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