Heart rhythm
Senolytic reduction of senescent cells mitigates atrial arrhythmia vulnerability in aging rabbits.
Elif Sengun, Lily Zhou, Maxfield Kelsey, Nilufer N Turan, Yichun Lu, Anatoli Y Kabakov, Peter Bronk, Eric Mi, Tae Yun Kim, Shilpa Vijayakumar, Dana Price, Sade Solola Nussbaum, Christopher Song, Jun Feng, Frank W Sellke
Published: 202610.1016/j.hrthm.2026.01.007
Abstract
BACKGROUND: Atrial fibrillation (AF) is the most common arrhythmia among the elderly and a major contributor to morbidity and mortality. Inflammation plays a central role in AF pathogenesis, and aging is a key independent risk factor. Cellular senesc…
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