Hematology/oncology clinics of North AmericaHumansFemaleGenital NeoplasmsMAP Kinase Signaling SystemMolecular Targeted Therapy
Mitogen-Activated Protein Kinase Driven Rare Gynecologic Cancers and Evolving Therapeutic Targets.
Rachel N Grisham, Aaron Praiss, Chrisann Kyi, Kay J Park
Published: 202510.1016/j.hoc.2025.04.015
Abstract
The mitogen-activated protein kinase (MAPK) cascade is a critical pathway involved in cancer cell survival as well as resistance to drug therapy. Phosphorylation of extracellular signal-regulated kinase 1 (ERK1) and extracellular signal-regulated kin…
Preview only. Read the full abstract at the source