Hearing researchCisplatinHumansAnimalsOtotoxicityAntineoplastic Agents
Bridging the gap: mechanisms and novel translational strategies to prevent cisplatin-induced ototoxicity.
Jie Bai, Wenjia Wang, Zeming Fu, Jingpu Yang, Yingyuan Guo, Guofang Guan
Published: 202610.1016/j.heares.2025.109487
Abstract
Cisplatin is a widely used chemotherapeutic agent, but its clinical utility is limited by dose-dependent ototoxicity, causing irreversible sensorineural hearing loss and significantly impairing quality of life, especially in pediatric patients. This…
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