GeneHumansFemaleDNA-Binding ProteinsCase-Control StudiesRad51 Recombinase
Integrated case-control and in silico analysis of DNA double-strand break repair gene variants (RAD51, XRCC2, XRCC3, XRCC4, and LIG4) for ovarian cancer susceptibility.
Harshavardhani Canchi Sistla, Arun Seshachalam, Krishna Kumar Rathnam, Taruna Rajagopal, Srikanth Talluri, Subaranjana Saravanaguru Vasanthi, Nageswara Rao Dunna
Published: 202610.1016/j.gene.2025.149989
Abstract
The contribution of low-penetrance DNA repair genes (DRGs) to ovarian cancer (OC) risk remains poorly understood. Variants in homologous recombination repair (HRR) and non-homologous end joining (NHEJ) pathway genes may influence genomic stability an…
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