GeneFerroptosisAnimalsMitochondriaMiceAmino Acid Transport System y+
Trolline attenuates diabetic vascular injury by regulating SLC7A11-mediated ferroptosis and mitochondrial dysfunction.
Wenbo Liu, Cuifang Lu, Bin Yang, Ying Liu, Jie Yan, Tingyu Song, Xiaofei Wang
Published: 202610.1016/j.gene.2025.149968
Abstract
AIMS: This study investigated the therapeutic potential of Trolline, a natural compound, for alleviating high-glucose (HG)-induced vascular endothelial ferroptosis and mitochondrial dysfunction via the cystine/glutamate antiporter solute carrier fami…
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