GeneAnimalsEvolutionMolecularSex-Determining Region Y ProteinSex Determination Processes
The Tolerated functional decline Model: Relaxed constraint in the molecular evolution of mammalian master Sex-Determining gene SRY.
Honoka Okuyama, Ayuka Tokunaga, Shun Hayashi, Kei Nakasako, Daisuke Tsukamoto, Takuya Matsuo, Kei Tamura, Michihiko Ito
Published: 202510.1016/j.gene.2025.149844
Abstract
While most genes are subject to strong purifying selection to maintain essential functions, some master sex-determining genes (MSDGs) appear to evolve under unexpectedly relaxed constraints. To understand the molecular mechanisms and evolutionary rat…
Preview only. Read the full abstract at the source