Fish & shellfish immunology
Japanese eel SOCS1 suppresses MyD88-mediated NF-κB activation: implications for negative regulation of innate immunity in teleosts.
Tianyu Wang, Peng Lin, Yilei Wang, Luis O B Afonso, Jianjun Feng
Published: 202610.1016/j.fsi.2026.111138
Abstract
Suppressor of cytokine signaling 1 (SOCS1) is a pivotal negative regulator of cytokine-mediated signaling in mammals, yet its role in teleost fish immunity remains poorly understood. In this study, we cloned and characterized the full-length SOCS1 cD…
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