Fish & shellfish immunologyMethicillin-Resistant Staphylococcus aureusAnimalsZebrafishCell MembraneRibosomes
Zebrafish yolk high phosphoprotein-derived peptide Pt5-1c inhibits methicillin-resistant Staphylococcus aureus by targeting the cell membrane with associated ribosomal perturbation.
Yazhuo Zhang, Jia Liu, Gehui Ren, Xueying Liu, Xiangyu Gaochen, Shaoting Shi, Huimin Duan
Published: 202610.1016/j.fsi.2025.111017
Abstract
Pt5-1c, an α-helical antibacterial peptide, is derived from zebrafish yolk high phosphoprotein, rich in positively charged and hydrophobic residues. Although the antibacterial effects of Pt5-1c against common Gram-negative/positive bacteria have been…
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