Fish & shellfish immunologyAnimalsZebrafishIronFish DiseasesZebrafish Proteins
LEAP2 deficiency does not impair essential iron-dependent functions in zebrafish.
Yueyue Fei, Chongyu Zhong, Ruiqin Hu, Min Wei, Jigang Lu, Yan Zhou
Published: 202610.1016/j.fsi.2025.110930
Abstract
LEAP2 is a blood-derived antimicrobial peptide predominantly expressed in the liver. As the first identified liver-derived blood antimicrobial peptide, LEAP1/hepcidin is a key regulator of iron metabolism. Although LEAP2 shares gene structure and tis…
Preview only. Read the full abstract at the source