Fish & shellfish immunologyAnimalsPerciformesMicroRNAsFish ProteinsGene Expression Regulation
MicroRNA-7565 negatively regulates the IL-4/13-mediated Th2 immune response by targeting IL-13Rα1 in large yellow croaker (Larimichthys crocea).
Huazhi Chen, Jiamei Liu, Wenxing Li, Jinqun Ao, Xinhua Chen, Yinnan Mu
Published: 202510.1016/j.fsi.2025.110912
Abstract
IL-4 and IL-13 are cytokines with structural homology, exerting critical functions in the Th2 immune response via binding to their respective receptor complexes and activating the MAPK and mTOR pathways. MicroRNAs (miRNAs) modulate diverse molecular…
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