Free radical biology & medicine
Chronic stress-induced steroids mediate mitochondrial fission and fibrosis in the trabecular meshwork via the MIEF1-MAOA complex.
Yilin Sun, Yingjian Sun, Mingxuan Wang, Zhibo Si, Zhaoying Zhang, Yajuan Zheng
Published: 202610.1016/j.freeradbiomed.2026.01.037
Abstract
Glaucoma remains the leading cause of irreversible blindness worldwide. Trabecular meshwork (TM) dysfunction, particularly fibrosis, is a major driver of elevated intraocular pressure (IOP). Although steroid-induced glaucoma is well established, the…
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