Free radical biology & medicine
Di(2-ethylhexyl) phthalate induces male reproductive toxicity through mitophagy-dependent ferroptosis of spermatocytes in mice.
Zhen Zhang, Hang Han, Liyang Ding, Hong Yang, Yu Deng, Yitong Shang, Tengjiao He, Xinru Cui, Bo Xu, Xufeng Fu
Published: 202610.1016/j.freeradbiomed.2026.01.014
Abstract
Di(2-ethylhexyl) phthalate (DEHP), a widely utilized plasticizer, impairs male reproductive function; however, the precise mechanisms underlying this effect have yet to be fully elucidated. This study investigates DEHP-induced spermatocyte toxicity a…
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