Free radical biology & medicine
Exosomes from young healthy human plasma ameliorate sepsis-induced cardiomyopathy by inhibiting ferroptosis via the miR-3130-3p/LPCAT3 axis.
Weiwei Wang, Zhenghui Wang, Fujie Wang, Ying Li, Haoyang Zhou, Yanan Pu, Xufeng Chen, Yi Jiang
Published: 202610.1016/j.freeradbiomed.2026.01.012
Abstract
BACKGROUND: Sepsis-induced cardiomyopathy (SICM) is one of the leading causes of mortality in sepsis patients, and currently, there are no effective treatments available. Ferroptosis has been proven to play a critical role in SICM. Exosomes from the…
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