Free radical biology & medicine
Spermidine promotes osteogenic differentiation of BMSCs via the m6A methylation-autophagy axis under inflammatory stress.
Lili Hao, Wenjie Zhang, Xiaoting Peng, Yujia Bai, Cheng Tian, Yiwen Zhang, Di Li, Zhihui Feng, Baoshan Xu, Qiong Xu
Published: 202610.1016/j.freeradbiomed.2025.12.057
Abstract
Disordered osteogenic potential in bone marrow mesenchymal stem cells (BMSCs) is a hallmark of inflammatory jaw diseases. Recent studies suggest that inflammatory stimulating disrupts energy metabolism during BMSC osteogenesis. However, the impact of…
Preview only. Read the full abstract at the source