Free radical biology & medicine
Nsun2-mediated m5C methylation of Ncor1 exacerbates sepsis-induced cardiomyopathy by promoting mitochondrial dysfunction.
Chan Chen, Qing Liu, Junmei Xu, Mengyuan Zi, Xinglan Chen, Feng Xiao
Published: 202510.1016/j.freeradbiomed.2025.12.056
Abstract
Sepsis-induced cardiomyopathy (SIC) is a severe complication of sepsis characterized by mitochondrial dysfunction and impaired myocardial contractility, yet its molecular pathogenesis remains incompletely understood. In this study, we demonstrate tha…
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