Free radical biology & medicine
Disrupted riboflavin metabolism impairs circadian rhythm in ovarian granulosa cells: a novel mechanism driving DOR.
Yao Peng, Zuojia Ma, Shuangyi Li, Donglai Hu, Jiayu Shi, Shimin Wu, Jie Chen, Yong Tan
Published: 202510.1016/j.freeradbiomed.2025.12.045
Abstract
Diminished ovarian reserve (DOR) is a major cause of female infertility and a significant indicator of reproductive aging, yet its underlying pathogenesis remains poorly understood. In this study, we initially assessed the expression of core circadia…
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