Free radical biology & medicine
Oxidative stress impairs the expansion of regulatory T cells in active vitiligo via dysregulated CGRP-RAMP1-Gαi3 signaling.
Shi-Jiao Zhang, Meng-Meng Geng, Qian-Wen Li, Xiao-Hui Li, You Zhou, Long-Fei Luo, Shan Jiang, Tie-Chi Lei
Published: 202510.1016/j.freeradbiomed.2025.12.041
Abstract
The Koebner phenomenon is a hallmark of active vitiligo, yet its underlying mechanisms remain unclear. Here, we investigated whether calcitonin gene-related peptide (CGRP), which is released from transient receptor potential vanilloid 1 (TRPV1)+ noci…
Preview only. Read the full abstract at the source