Free radical biology & medicineHumansFerroptosisNF-E2-Related Factor 2Colorectal NeoplasmsHippo Signaling Pathway
SLC38A5 drives colorectal cancer ferroptosis resistance through the Hippo-YAP/Nrf2 axis.
Xing Zhang, Jiaqi Zhang, Haifeng Peng, Xiaofan Liu, Hongsheng Zhang
Published: 202610.1016/j.freeradbiomed.2025.12.020
Abstract
Colorectal cancer (CRC), a malignancy characterized by high aggressiveness, metastatic propensity, frequent recurrence, and poor prognosis, underscores the critical need for identifying biomarkers to guide targeted therapeutic strategies. Solute carr…
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