Free radical biology & medicineAnimalsGlutamineHumansNF-E2-Related Factor 2Mice
The role of glutamine/Nrf2-enhanced PHGDH in Cadmium-induced lactate utilization.
Yuxin Pang, Shengnan Li, Qingxuan Zhang, Yuting Liu, Ying Kong, Jun Cao
Published: 202610.1016/j.freeradbiomed.2025.12.015
Abstract
Cadmium (Cd) is a toxic heavy metal that is closely associated with the occurrence and progression of lung cancer. Our previous studies showed that Cd promoted lactate utilization and the expression of phosphoglycerate dehydrogenase (PHGDH), which is…
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