Free radical biology & medicineHumansSpace FlightOxidation-ReductionOxidative StressOsteoporosis
Redox-regulated bone loss in spaceflight and terrestrial models: Molecular mechanisms and therapeutic strategies.
Gianfranco Pintus, Mohammed A Akram, Roberta Giordo, Gianfilippo Caggiari, Amin F Majdalawieh
Published: 202610.1016/j.freeradbiomed.2025.11.048
Abstract
Exposure to microgravity induces a rapid and profound loss of bone mass, particularly in weight-bearing skeletal regions, closely resembling accelerated osteoporosis on Earth. Traditionally attributed to mechanical unloading, bone loss in space is no…
Preview only. Read the full abstract at the source