Free radical biology & medicineOxidative StressHumansAnimalsVascular RemodelingTrans-Activators
Epigenetically activated MIR100HG regulates UPF1-mediated oxidative stress to promote pulmonary vascular immune microenvironment remodeling.
Langlin Ou, Yingli Chen, Ao Shen, Siyu He, Jian Mei, Zitong Meng, Hao Yuan, Xiaoying Wang, Xiangrui Zhu, Lixin Zhang, Yan Xing, Fei Li, Song Wang, Xiangming Pang, Yuxiang Liu
Published: 202610.1016/j.freeradbiomed.2025.11.038
Abstract
Oxidative stress is positively associated with vascular remodeling and immune microenvironment imbalance in pulmonary hypertension (PH). However, the precise molecular mechanisms involving epigenetic modifications in this process remain unclear. The…
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