Free radical biology & medicineVitiligoOximesOxidative StressMelanocytesHumans
6-Bromo-Indirubin-3'-Oxime (6BIO) mitigates oxidative stress and immune dysregulation to promote melanocyte regeneration in vitiligo.
Himani Sharma, Harjot Kaur, Hitaishi Kaushik, Prakshi Sharma, Vinod Kumar, Davinder Parsad, Ravinder Kumar
Published: 202610.1016/j.freeradbiomed.2025.11.023
Abstract
BACKGROUND: 6-bromo-indirubin-3-oxime (6BIO) is a small compound with known antioxidative and immunomodulatory properties, yet its efficacy in vitiligo remains unexplored. OBJECTIVES: To investigate therapeutic potential of 6BIO in modulating oxidati…
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