Free radical biology & medicineAnimalsTriclosanRatsMitochondriaBrain
The effect of triclosan uncovers the possible involvement of complex II in the oxidation of glycerol-3-phosphate in brain mitochondria.
Alexey G Kruglov, Anna B Nikiforova, Marina V Akulenko
Published: 202610.1016/j.freeradbiomed.2025.11.008
Abstract
Mitochondrial glycerol-3-phosphate dehydrogenase (mGPDH) links the oxidative phosphorylation, glycolysis, and phospholipid biosynthesis and essentially contributes to ROS production by mitochondria in certain tissues. The pattern of biological effect…
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