Free radical biology & medicineAnimalsRANK LigandOvariectomyOsteogenesisOsteoclasts
Corosolic acid modulates RANKL-triggered signaling to suppress osteoclastogenesis and ovariectomy-induced bone loss.
Chuanyong Zhao, Fanghui Wu, Liben Zhao, Jiangtao Zhong, Chenhao Huang, Zhangchi Jiang, Jingqi Zheng, Shengwu Yang, Chunwu Zhang, Lei Zhang
Published: 202510.1016/j.freeradbiomed.2025.10.284
Abstract
Osteoporosis is typified by increased bone degradation mediated through osteoclast activity, necessitating innovative interventions. This research explores the therapeutic efficacy of corosolic acid (CA), a triterpenoid recognized for its antioxidati…
Preview only. Read the full abstract at the source