Free radical biology & medicineAnimalsOxidative StressPolymersRatsIndoles
How do particle size, dosage, and exposure duration influence oxidative stress parameters and the in vivo toxicological profile of polydopamine nanoparticles?
Marta Szukalska, Radosław Mrówczyński, Patrycja Sujka-Kordowska, Izabela Miechowicz, Tomasz Zalewski, Bartosz F Grześkowiak, Magdalena J Bigaj-Józefowska, Michał Nowicki, Ewa Florek
Published: 202610.1016/j.freeradbiomed.2025.10.265
Abstract
This study assessed the toxicity and changes in oxidative stress biomarkers in plasma and organs of rats treated with manganese-modified polydopamine nanoparticles (PDA@Mn NPs). In vivo MRI experiments demonstrated that our nanoparticles exhibit stro…
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