Free radical biology & medicineLuteolinAnimalsPeriodontitisNF-E2-Related Factor 2Mice
Luteolin as a multi-target agent against periodontitis: integrating Nrf2-mediated antioxidant defense and quorum sensing interference.
Zixin Fan, Pengzhou Tang, Yuluan Bu, Hancheng Zhou, Yan Xu, Lu Li
Published: 202610.1016/j.freeradbiomed.2025.10.261
Abstract
AIM OF THE STUDY: This study integrated in vivo and in vitro approaches to elucidate the molecular mechanisms of luteolin against periodontitis, which involved activating the PI3K/AKT/Nrf2 pathway to restore mitochondrial function and alleviate oxida…
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