Free radical biology & medicineAnimalsFerroptosisReperfusion InjuryAcute Kidney InjuryMice
Reticulon 3 deficiency induces ferroptosis via chaperone-mediated autophagy in ischemia-reperfusion induced acute kidney injury.
Yingying Zhang, Hao Huang, Nannan Li, Yi Dong, Meifang Zhao, Siyuan Zhang, Wenzhe She, Jishi Liu, Rong Xiang
Published: 202610.1016/j.freeradbiomed.2025.10.256
Abstract
Acute kidney injury (AKI) represents a critical clinical syndrome characterized by abrupt deterioration of renal function. Ischemia-reperfusion injury (IRI) constitutes the predominant etiology of AKI, where renal hypoperfusion triggers tubular epith…
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