Food research international (Ottawa, Ont.)HumansApoptosisProto-Oncogene Proteins c-aktGlycolysisColorectal Neoplasms
Drimartol B suppresses AKT1-mediated glycolysis to trigger apoptosis in colorectal cancer.
Jiwen Li, Zhongyu Li, Mengru Cui, Mei Sun, Lei Men, Xiaojie Gong, Wentao Su, Keke Li
Published: 202610.1016/j.foodres.2025.118077
Abstract
Colorectal cancer (CRC) persists as a formidable therapeutic challenge, necessitating the urgent discovery of innovative treatment modalities. This study reports, for the first time, the anti-CRC activity of drimartol B, a bioactive sesquiterpene iso…
Preview only. Read the full abstract at the source