Food research international (Ottawa, Ont.)TanninsCopperHumansSerum AlbuminHuman
Role of predicted tannic acid deprotonation sites in Cu(II) coordination and human serum albumin interaction: Density functional theory and spectroscopic investigation.
Qinhao Guan, Yaying Cao, Yue Zhang, Baiyi Zhou, Jiayu Wang, Xuewei Yang, Denis Baranenko, Alejandro Cifuentes, Elena Ibañez, Weihong Lu
Published: 202510.1016/j.foodres.2025.117798
Abstract
The bioavailability of dietary polyphenols is critically dependent on their interaction with transport proteins like human serum albumin (HSA), yet how this process is modulated by metal ions remains poorly understood. This study elucidates the modul…
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