Food research international (Ottawa, Ont.)AnimalsDietHigh-FatUmbelliferonesProto-Oncogene Proteins c-akt
Esculetin improves lipid metabolism disorders induced by a high-fat diet by regulating the P13K-AKT signaling pathway and taurocholic acid metabolism.
Liyang Guo, Yongjie Zhang, Kun Wang, Shun Wang, Yecheng Yao, Weiqi Liu, Fuhua Gu, Yifan Li, Rui Li, Jichang Li, Chunli Chen
Published: 202510.1016/j.foodres.2025.117281
Abstract
High-fat diet (HFD)-induced lipid metabolism disorders are significant pathogenic factors in the development of various chronic diseases associated with metabolic dysfunction, posing a serious threat to public health. Esculetin (EL) is characterized…
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